Levers to optimize the IVT reaction for increased mRNA yield

Levers to optimize the IVT reaction for increased mRNA yield

First Name

Last Name

Business Email Address

Job Title

Company Name

Address

Country

Mobile Phone

Postal Code

Are you or your group involved in mRNA in vitro transcription (IVT)

What are your main concerns regarding your IVT reaction?

Yield

dsRNA

Quality of raw materials (GMP / AOF)

Full length mRNA

Impurities from the raw materials

Capping of your mRNA

Other

In what stage of the mRNA production lifecycle are you working?

Process development

Analytical

Pre-clinical

Clinical trials

Commercial production

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In vitro synthesis of single-stranded mRNA molecules is a widely used laboratory procedure that is central to RNA research and therapeutic development. It is therefore important to know the critical factors that influence the in vitro transcription (IVT) reaction.

This guide summarizes some of the tools that can be used to set up and optimize the IVT reaction for enhanced mRNA yield. Read further to learn more...